M6 | Integrative action of the sensorimotor system – Cerebellum & Basal ganglia

Clinical Signs of Cerebellar Damage

 

 

Ataxia

Syndrome characterized by a breakdown of movement coordination and inaccuracies when reaching for a visual target.  Ataxia includes:

  • Dysmetria (inaccurate movement amplitudes)
  • Asynergia (poor coordination between joints, decomposition of movement)
  • Intention tremor
  • Dysdiadochokinesia (inability to perform rapidly alternating movements smoothly)
  • Hypotonia and pendular knee jerks.

 


Kaltura Mediaspace

 


Kaltura Mediaspace

 


Kaltura Mediaspace

 


Kaltura Mediaspace

 


Kaltura Mediaspace

 

Localization of function (somatotopic organization)

Lesions in intermediate and lateral CB give rise to ataxia of individual limbs; lesions in medial CB results in poor equilibrium and falling, ataxia of gait (walking).

CB damage prevents modification and adaptation of behaviors, that is, it has a function in motor learning.

References

  • Voogd, J., & Glickstein, M. (1998). The anatomy of the cerebellum. Trends in Neurosciences., 21(9), 370-375. [PDF]
  • Glickstein, M. (2000). How are visual areas of the brain connected to motor areas for the sensory guidance of movement? Trends in Neurosciences., 23(12), 613-617. [PDF]
  • Glickstein, M. (2007). What does the cerebellum really do? Current Biology, 17(19), R824-827. [PDF]

License

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KINES 531: Neural Control of Movement by Peter L.E. van Kan is licensed under a Creative Commons Attribution 4.0 International License, except where otherwise noted.

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