Refer to the general guidelines for Mini Lab Reports on Canvas, found here (link opens in a new tab): Mini Lab Report Guidelines

Introduction (draft 2)

This week, you will write a second draft of the Introduction section for your final lab report. Consider the feedback that you and your partner each received on the first draft of the Introduction in Mini Lab Report 2.

Your Introduction should be 2 double-spaced pages long.

The introduction provides the context for your report by summarizing what is currently known about your topic and stating the hypotheses or questions you are studying. The introduction should briefly describe the rationale of the work and the approach you took. Use the active voice. When presenting published information, use the present tense (i.e. this is what we currently know). Introductions start out with a description of the general background about the problem and focus down to the specific problem you are studying.

Your introduction should address the following:

  1. What is the protein you are working on and why is it interesting to the general public?
  2. Provide molecular details about HCAII that are relevant to your mutation. Including a helpful figure of wild type HCAII is up to your discretion.
  3. Clearly state your hypothesis. The statement of your hypothesis should flow naturally from the information you’ve provided so far. Be sure to consider the feedback you received during your in-lab presentation. Including information from the sequence alignment here is at your discretion.
  4. Give a general description of the experiments you used to address your hypothesis. (You have not done the experiments yet… but pretend that you have, and write in the past tense.)
  5. Throughout this section you should use 4–5 literature sources (at least 3 from the primary literature). Be sure to reference all of your sources.


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Biochemistry 551 (Online Version) Lab Manual Copyright © by Lynne PROST is licensed under a Creative Commons Attribution 4.0 International License, except where otherwise noted.

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